/*! tailwindcss v4.2.1 | MIT License | https://tailwindcss.com */
@layer theme{:root,:host{--font-sans:ui-sans-serif, system-ui, sans-serif, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", "Noto Color Emoji";--font-mono:ui-monospace, SFMono-Regular, Menlo, Monaco, Consolas, "Liberation Mono", "Courier New", monospace;--spacing:.25rem;--default-font-family:var(--font-sans);--default-mono-font-family:var(--font-mono)}}@layer base{*,:after,:before{box-sizing:border-box;border:0 solid;margin:0;padding:0}::backdrop{box-sizing:border-box;border:0 solid;margin:0;padding:0}::file-selector-button{box-sizing:border-box;border:0 solid;margin:0;padding:0}html,:host{-webkit-text-size-adjust:100%;tab-size:4;line-height:1.5;font-family:var(--default-font-family,ui-sans-serif, system-ui, sans-serif, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", "Noto Color Emoji");font-feature-settings:var(--default-font-feature-settings,normal);font-variation-settings:var(--default-font-variation-settings,normal);-webkit-tap-highlight-color:transparent}hr{height:0;color:inherit;border-top-width:1px}abbr:where([title]){-webkit-text-decoration:underline dotted;text-decoration:underline dotted}h1,h2,h3,h4,h5,h6{font-size:inherit;font-weight:inherit}a{color:inherit;-webkit-text-decoration:inherit;-webkit-text-decoration:inherit;-webkit-text-decoration:inherit;-webkit-text-decoration:inherit;text-decoration:inherit}b,strong{font-weight:bolder}code,kbd,samp,pre{font-family:var(--default-mono-font-family,ui-monospace, SFMono-Regular, Menlo, Monaco, Consolas, "Liberation Mono", "Courier New", monospace);font-feature-settings:var(--default-mono-font-feature-settings,normal);font-variation-settings:var(--default-mono-font-variation-settings,normal);font-size:1em}small{font-size:80%}sub,sup{vertical-align:baseline;font-size:75%;line-height:0;position:relative}sub{bottom:-.25em}sup{top:-.5em}table{text-indent:0;border-color:inherit;border-collapse:collapse}:-moz-focusring{outline:auto}progress{vertical-align:baseline}summary{display:list-item}ol,ul,menu{list-style:none}img,svg,video,canvas,audio,iframe,embed,object{vertical-align:middle;display:block}img,video{max-width:100%;height:auto}button,input,select,optgroup,textarea{font:inherit;font-feature-settings:inherit;font-variation-settings:inherit;letter-spacing:inherit;color:inherit;opacity:1;background-color:#0000;border-radius:0}::file-selector-button{font:inherit;font-feature-settings:inherit;font-variation-settings:inherit;letter-spacing:inherit;color:inherit;opacity:1;background-color:#0000;border-radius:0}:where(select:is([multiple],[size])) optgroup{font-weight:bolder}:where(select:is([multiple],[size])) optgroup option{padding-inline-start:20px}::file-selector-button{margin-inline-end:4px}::placeholder{opacity:1}@supports (not ((-webkit-appearance:-apple-pay-button))) or (contain-intrinsic-size:1px){::placeholder{color:currentColor}@supports (color:color-mix(in lab, red, red)){::placeholder{color:color-mix(in oklab, currentcolor 50%, transparent)}}}textarea{resize:vertical}::-webkit-search-decoration{-webkit-appearance:none}::-webkit-date-and-time-value{min-height:1lh;text-align:inherit}::-webkit-datetime-edit{display:inline-flex}::-webkit-datetime-edit-fields-wrapper{padding:0}::-webkit-datetime-edit{padding-block:0}::-webkit-datetime-edit-year-field{padding-block:0}::-webkit-datetime-edit-month-field{padding-block:0}::-webkit-datetime-edit-day-field{padding-block:0}::-webkit-datetime-edit-hour-field{padding-block:0}::-webkit-datetime-edit-minute-field{padding-block:0}::-webkit-datetime-edit-second-field{padding-block:0}::-webkit-datetime-edit-millisecond-field{padding-block:0}::-webkit-datetime-edit-meridiem-field{padding-block:0}::-webkit-calendar-picker-indicator{line-height:1}:-moz-ui-invalid{box-shadow:none}button,input:where([type=button],[type=reset],[type=submit]){-webkit-appearance:button;appearance:button}::file-selector-button{-webkit-appearance:button;appearance:button}::-webkit-inner-spin-button{height:auto}::-webkit-outer-spin-button{height:auto}[hidden]:where(:not([hidden=until-found])){display:none!important}}@layer components;@layer utilities{.relative{position:relative}.start{inset-inline-start:var(--spacing)}.table{display:table}.antialiased{-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale}}:root{--ink:#09253a;--muted:#607180;--teal:#00b9a7;--teal-dark:#058a83;--blue:#00699a;--coral:#e16f62;--paper:#f4f7f6;--line:#dce5e3;--white:#fff}*{box-sizing:border-box}html{scroll-behavior:smooth}body{background:var(--paper);color:var(--ink);margin:0;font-family:Arial,Helvetica,sans-serif}button,input{font:inherit}button{cursor:pointer}main{background:radial-gradient(circle at 85% 8%,#00b9a71f,transparent 25%),var(--paper);min-height:100vh;overflow:hidden}.site-header{border-bottom:1px solid #09253a1a;justify-content:space-between;align-items:center;max-width:1480px;margin:0 auto;padding:22px 42px;display:flex}.brand{color:var(--ink);align-items:center;gap:18px;text-decoration:none;display:flex}.brand img{width:172px;height:auto;display:block}.product-name{border-left:1px solid var(--line);letter-spacing:-.02em;padding-left:18px;font-weight:700}.data-pill{border:1px solid var(--line);color:var(--muted);background:#ffffffb8;border-radius:99px;align-items:center;gap:9px;padding:9px 13px;font-size:12px;font-weight:700;display:inline-flex}.data-pill i{background:var(--teal);border-radius:50%;width:7px;height:7px;box-shadow:0 0 0 4px #00b9a71f}.hero{grid-template-columns:minmax(0,1.65fr) minmax(280px,.7fr);align-items:end;gap:68px;max-width:1480px;margin:0 auto;padding:72px 42px 44px;display:grid}.eyebrow,.kicker{color:var(--teal-dark);letter-spacing:.18em;margin:0 0 15px;font-size:11px;font-weight:800;line-height:1}h1{letter-spacing:-.065em;max-width:900px;margin:0;font-size:clamp(52px,6.2vw,96px);font-weight:750;line-height:.96}h1 span{color:var(--teal-dark)}.hero-copy{max-width:750px;color:var(--muted);margin:28px 0 0;font-size:19px;line-height:1.6}.hero-note{border-left:2px solid var(--teal);padding:23px 0 8px 24px}.hero-note strong{text-transform:uppercase;letter-spacing:.1em;font-size:13px}.hero-note p{color:var(--muted);margin:10px 0 0;font-size:14px;line-height:1.6}.explorer-shell{background:var(--white);border:1px solid var(--line);border-radius:26px;grid-template-columns:330px minmax(0,1fr);width:min(1480px,100% - 84px);margin:0 auto 72px;display:grid;overflow:hidden;box-shadow:0 28px 70px #09253a17}.control-panel{color:#fff;background:#0b2b40;padding:34px 30px}.panel-heading{border-bottom:1px solid #ffffff1f;margin-bottom:8px;padding-bottom:25px}.panel-heading .kicker{color:#67d8cb}.panel-heading h2,.evidence-topline h2{letter-spacing:-.035em;margin:0;font-size:25px}.panel-heading p:last-child{color:#a9bbc6;margin:11px 0 0;font-size:13px;line-height:1.5}.control{border-bottom:1px solid #ffffff17;padding:16px 0 11px;display:block}.control>span{justify-content:space-between;align-items:center;gap:15px;display:flex}.control b{font-size:13px}.control output{color:#78ded3;font-size:12px;font-weight:700}.control input{width:100%;accent-color:var(--teal);margin-top:13px}.simulate-button{background:var(--teal);color:#052d31;border:0;border-radius:12px;justify-content:space-between;align-items:center;width:100%;margin-top:24px;padding:15px 17px;font-weight:800;transition:transform .2s,background .2s;display:flex}.simulate-button:hover{background:#33c9ba;transform:translateY(-2px)}.assumption-note,.privacy-note{color:#a8bdc8;margin:13px 4px 0;font-size:10px;line-height:1.5}.privacy-note{color:#8fa6b4;margin-top:6px}.evidence-panel{min-width:0;padding:34px}.evidence-topline{justify-content:space-between;align-items:center;gap:24px;display:flex}.evidence-topline .kicker{margin-bottom:8px}.view-toggle{background:#eef3f2;border-radius:10px;gap:4px;padding:4px;display:flex}.view-toggle button{color:var(--muted);background:0 0;border:0;border-radius:8px;padding:9px 12px;font-size:12px;font-weight:700}.view-toggle button.active{color:var(--ink);background:#fff;box-shadow:0 3px 10px #09253a14}.metrics-grid{grid-template-columns:repeat(3,1fr);gap:12px;margin:25px 0 24px;display:grid}.metric{border:1px solid var(--line);border-radius:14px;min-width:0;padding:17px 18px;position:relative;overflow:hidden}.metric:before{content:"";background:var(--teal);width:3px;position:absolute;inset:0 auto 0 0}.metric.coral:before{background:var(--coral)}.metric.blue:before{background:var(--blue)}.metric p{color:var(--muted);text-transform:uppercase;letter-spacing:.07em;margin:0 0 8px;font-size:11px;font-weight:700}.metric strong{letter-spacing:-.045em;font-size:28px}.metric span{color:var(--muted);margin-left:7px;font-size:11px}.timeline-card,.waterfall-card{border:1px solid var(--line);background:linear-gradient(#fbfdfd,#f4f8f7);border-radius:16px;min-height:390px;padding:21px 22px}.chart-labels{color:#8697a1;letter-spacing:.13em;grid-template-columns:55px 1fr;font-size:9px;font-weight:800;display:grid}.axis{color:#94a4ad;justify-content:space-between;margin:8px 46px 8px 55px;font-size:9px;display:flex}.timeline-rows{gap:5px;display:grid}.timeline-row{grid-template-columns:45px 1fr 42px;align-items:center;gap:10px;min-height:20px;display:grid}.patient-id,.change-value{color:#6f818c;font-size:9px;font-weight:700}.change-value{text-align:right;color:var(--ink)}.track{background:#e4ecea;border-radius:8px;height:9px;position:relative}.duration-bar{opacity:.85;transform-origin:0;background:#226e92;border-radius:8px;height:100%;animation:.7s both grow}.duration-bar.dose-2{background:#00a694}.duration-bar.dose-3{background:#7d7fb8}.duration-bar.dose-4{background:#c17b65}.event{background:var(--teal);border-radius:50%;width:8px;height:8px;position:absolute;top:50%;transform:translate(-50%,-50%);box-shadow:0 0 0 2px #fff}.event.toxicity{background:var(--coral);border-radius:2px;transform:translate(-50%,-50%)rotate(45deg)}.legend{border-top:1px solid var(--line);color:var(--muted);flex-wrap:wrap;gap:10px 17px;margin-top:15px;padding-top:14px;font-size:10px;display:flex}.legend span{align-items:center;gap:6px;display:inline-flex}.legend-dot{background:var(--teal);border-radius:50%;width:7px;height:7px}.legend-dot.toxicity{background:var(--coral);border-radius:1px;transform:rotate(45deg)}.legend-line{background:#226e92;border-radius:4px;width:17px;height:4px}.legend-line.dose-1{background:#226e92}.legend-line.dose-2{background:#00a694}.legend-line.dose-3{background:#7d7fb8}.legend-line.dose-4{background:#c17b65}.waterfall-card{min-height:390px;padding:30px 28px 36px 66px;position:relative;overflow:hidden}.waterfall-bars{z-index:2;align-items:center;gap:5px;height:280px;display:flex;position:relative}.waterfall-column{flex:1;justify-content:center;align-items:center;height:100%;display:flex}.waterfall-bar{transform-origin:bottom;border-radius:3px 3px 0 0;width:100%;min-width:6px;max-width:34px;animation:.6s both rise}.waterfall-bar.negative{background:var(--teal-dark);border-radius:0 0 3px 3px;transform:translateY(50%)}.waterfall-bar.positive{background:var(--coral);transform:translateY(-50%)}.waterfall-axis{color:#84949e;border-top:1px dashed #cbd7d4;font-size:9px;position:absolute;left:14px;right:18px}.waterfall-axis.upper{top:42px}.waterfall-axis.zero{color:var(--ink);border-color:#899da5;top:169px}.waterfall-axis.threshold{color:var(--teal-dark);border-color:#00a6948c;top:246px}.chart-caption{color:var(--muted);margin:0;font-size:10px;position:absolute;bottom:12px;left:66px}.signal-callout{background:#e9f5f2;border-radius:13px;grid-template-columns:35px 1fr;align-items:center;gap:15px;margin-top:16px;padding:17px 19px;display:grid}.signal-index{color:var(--teal-dark);font-size:11px;font-weight:900}.signal-callout p{color:#526872;margin:0;font-size:12px;line-height:1.5}.signal-callout strong{color:var(--ink)}.signals-card{border:1px solid var(--line);background:linear-gradient(145deg,#f9fcfb,#eef5f3);border-radius:16px;min-height:390px;padding:24px}.signals-heading{justify-content:space-between;align-items:flex-start;gap:20px;display:flex}.signals-heading h3{letter-spacing:-.035em;max-width:650px;margin:0;font-size:22px;line-height:1.25}.signals-heading>span{border:1px solid var(--line);color:var(--muted);white-space:nowrap;border-radius:99px;padding:7px 10px;font-size:10px;font-weight:700}.signal-lanes{gap:11px;margin-top:25px;display:grid}.signal-lane{grid-template-columns:120px 1fr;align-items:center;gap:14px;display:grid}.lane-label{color:var(--muted);align-items:center;gap:8px;font-size:11px;font-weight:700;display:flex}.lane-label i{background:var(--teal);border-radius:50%;width:8px;height:8px}.lane-label i.blue{background:var(--blue)}.lane-label i.coral{background:var(--coral)}.lane-track{border:1px solid var(--line);background:#ffffffdb;border-radius:9px;height:56px;position:relative;overflow:hidden}.lane-midline{border-top:1px dashed #d1dcda;position:absolute;top:50%;left:0;right:0}.lane-point{background:var(--teal);border-radius:50%;width:9px;height:9px;position:absolute;transform:translate(-50%,-50%);box-shadow:0 0 0 3px #00b9a721}.lane-point.blue{background:var(--blue);box-shadow:0 0 0 3px #00699a1f}.lane-point.coral{background:var(--coral);box-shadow:0 0 0 3px #e16f6221}.alignment-note{color:#fff;background:#0b2b40;border-radius:11px;grid-template-columns:110px 1fr;gap:13px;margin-top:19px;padding:16px 18px;display:grid}.alignment-note b{text-transform:uppercase;letter-spacing:.08em;color:#64d9cc;font-size:11px}.alignment-note p{color:#b8c9d1;margin:0;font-size:11px;line-height:1.55}.interpretation-section{max-width:1480px;margin:0 auto;padding:75px 42px 90px}.section-heading{grid-template-columns:1.2fr .8fr;align-items:end;column-gap:70px;display:grid}.section-heading .eyebrow{grid-column:1/-1}.section-heading h2{letter-spacing:-.055em;max-width:760px;margin:0;font-size:clamp(38px,4.5vw,68px);line-height:1.02}.section-heading>p:last-child{color:var(--muted);margin:0;font-size:16px;line-height:1.65}.question-grid{border-top:1px solid var(--line);grid-template-columns:repeat(3,1fr);margin-top:50px;display:grid}.question-grid article{border-right:1px solid var(--line);min-height:220px;padding:28px 28px 22px 0}.question-grid article+article{padding-left:28px}.question-grid article:last-child{border-right:0}.question-grid span{color:var(--teal-dark);font-size:11px;font-weight:900}.question-grid h3{letter-spacing:-.03em;margin:38px 0 13px;font-size:22px}.question-grid p{color:var(--muted);margin:0;font-size:14px;line-height:1.65}.cta-section{color:#fff;background:radial-gradient(circle at 90% 20%,#00b9a733,#0000 30%),#09253a;border-radius:24px;grid-template-columns:1.2fr .8fr;align-items:end;gap:70px;max-width:1396px;margin:0 auto 32px;padding:56px 58px;display:grid}.cta-section .eyebrow{color:#69d9cd}.cta-section h2{letter-spacing:-.05em;max-width:760px;margin:0;font-size:clamp(38px,4vw,61px);line-height:1.04}.cta-section>div:last-child p{color:#b9c9d2;margin:0 0 25px;line-height:1.65}.cta-section a{background:var(--teal);color:#062f33;border-radius:10px;justify-content:space-between;gap:38px;width:fit-content;padding:15px 18px;font-size:13px;font-weight:900;text-decoration:none;display:flex}footer{max-width:1480px;color:var(--muted);justify-content:space-between;gap:20px;margin:0 auto;padding:25px 42px 34px;font-size:11px;display:flex}footer a{color:var(--ink);font-weight:700;text-decoration:none}@keyframes grow{0%{opacity:.2;transform:scaleX(.05)}}@keyframes rise{0%{opacity:.2;height:0}}@media (max-width:980px){.hero{grid-template-columns:1fr;gap:24px}.hero-note{max-width:600px}.explorer-shell{grid-template-columns:1fr}.control-panel{grid-template-columns:repeat(2,1fr);gap:0 22px;display:grid}.panel-heading,.simulate-button,.privacy-note{grid-column:1/-1}.section-heading,.cta-section{grid-template-columns:1fr;gap:28px}.section-heading>p:last-child{max-width:720px}}@media (max-width:640px){.site-header{padding:17px 20px}.brand img{width:138px}.product-name{display:none}.data-pill{padding:7px 9px;font-size:9px}.hero{padding:46px 20px 30px}h1{font-size:51px}.hero-copy{font-size:16px}.explorer-shell{border-radius:18px;width:calc(100% - 24px);margin-bottom:32px}.control-panel{grid-template-columns:1fr;padding:28px 22px}.evidence-panel{padding:24px 15px}.evidence-topline{flex-direction:column;align-items:flex-start}.view-toggle{width:100%;overflow-x:auto}.view-toggle button{white-space:nowrap;flex:1}.metrics-grid{grid-template-columns:1fr}.timeline-card{padding:17px 12px;overflow-x:auto}.timeline-row,.chart-labels,.axis{min-width:500px}.waterfall-card{padding-left:52px}.signals-card{padding:19px 14px}.signals-heading{flex-direction:column}.signal-lane,.alignment-note{grid-template-columns:1fr}.interpretation-section{padding:54px 20px}.question-grid{grid-template-columns:1fr}.question-grid article,.question-grid article+article{border-right:0;border-bottom:1px solid var(--line);min-height:0;padding:25px 0}.question-grid article:last-child{border-bottom:0}.question-grid h3{margin-top:19px}.cta-section{margin:0 12px 20px;padding:38px 24px}.cta-section h2{font-size:39px}footer{flex-direction:column;padding:24px 20px}}@media (prefers-reduced-motion:reduce){*,:before,:after{scroll-behavior:auto!important;animation-duration:.01ms!important}}